What is the role of linezolid in the treatment of mycobacterium chelonae infection?

Updated: Dec 20, 2018
  • Author: Alfred Scott Lea, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Linezolid has good in vitro activity against M chelonae, and greater than 50% of isolates have susceptible MICs. [25, 29, 45] It has been shown to be successful in treatment, and, similar to tigecycline, it is usually considered when other options have been exhausted owing to the expense and risk of toxicity with long-term therapy. [46, 47] The authors do not recommend linezolid therapy for treatment durations of more than 4 weeks if it can be avoided, owing to unacceptable toxicities.


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