What is the prognosis of mycobacterium chelonae infection?

Updated: Dec 20, 2018
  • Author: Alfred Scott Lea, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

With debridement and antibiotic therapy guided by susceptibility data, the prognosis is very good for most infections. Prognosis is worse if the patient is immunocompromised or noncompliant with therapy, which can be prolonged and poorly tolerated.

Lung disease may be difficult or impossible to eradicate. Chronic suppression of the infection and slowing of lung disease progression may be the only achievable goals in this setting.

Cure of infected implants that cannot be removed may be impossible and require antimicrobial suppressive therapy. Infection of cosmetic implants and procedures can be disfiguring.

Unacceptable toxicities with prolonged antibiotic use may develop, particularly with linezolid (lactic acidosis, neuropathy, myelosuppression), aminoglycosides (renal failure, hearing loss, tinnitus), and fluoroquinolones (tendon rupture).


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