What are the treatment options for peroneal nerve entrapment?

Updated: Oct 15, 2019
  • Author: Minoo Hadjari Hollis, MD; Chief Editor: Thomas M DeBerardino, MD  more...
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NSAIDs or oral corticosteroids may be useful in cases where an inflammatory process is present. Corticosteroids injected into the affected region may reduce swelling and pressure on the nerve in some cases. Symptomatic pharmacologic treatment may consist of TCAs (eg, amitriptyline) or neuroleptic medications (eg, gabapentin and carbamazepine).

A brace (ankle-foot orthosis [AFO]), splints, or orthopedic shoes may control the abnormal dynamics at the ankle and provide dorsiflexion assistance for a more ideal gait pattern during nerve recovery. In-shoe orthotics may be helpful in certain instances, as in the correction of a biomechanical malalignment in gait (eg, in patients with severe flatfoot or cavus foot).

Many authors have reported spontaneous recovery; therefore, initial nonoperative management for a minimum of 3-4 months is recommended for idiopathic cases and for those suggestive of neurapraxia.

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