What is the pathogenesis of lateral femoral cutaneous nerve entrapment?

Updated: Oct 15, 2019
  • Author: Minoo Hadjari Hollis, MD; Chief Editor: Thomas M DeBerardino, MD  more...
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Entrapment of the lateral femoral cutaneous nerve usually occurs at the inguinal ligament. The peak incidence for this condition is in middle age. Differential diagnoses include lumbar radiculopathies and discogenic or nerve root problems at L2 and L3. The entrapment may be from intrapelvic causes, extrapelvic causes, or mechanical causes.

Intrapelvic causes include pregnancy, abdominal tumors, uterine fibroids, diverticulitis, or appendicitis. Injury has been described in cases of abdominal aortic aneurysm. Extrapelvic causes include trauma to the region of the ASIS (eg, from a seatbelt in a motor vehicle accident), tight garments, belts, girdles, or stretching from obesity and ascites. Mechanical factors include prolonged sitting or standing and pelvic tilt from leg-length discrepancy. Diabetes can also cause this neuropathy in isolation or in the setting of a polyneuropathy.

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