How is acquired toxoplasmosis distinguished from Epstein-Barr virus (EBV) infectious mononucleosis (mono)?

Updated: Sep 20, 2018
  • Author: Burke A Cunha, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Acquired toxoplasmosis in adults has minimal pharyngeal or hepatic involvement, but adenopathy may be prominent. In contrast to EBV infectious mononucleosis, generalized adenopathy is not a feature of toxoplasmosis. Highly characteristic of toxoplasmosis is asymmetrical lymphadenopathy limited to an isolated lymph node group. Patients with toxoplasmosis have little or no fever, fatigue, or pharyngitis, which helps differentiate toxoplasmosis-induced infectious mononucleosis from EBV-induced infectious mononucleosis.


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