How is posterior oropharynx characterized in patients with Epstein-Barr virus (EBV) infectious mononucleosis (mono) and how does it compare with the findings in chronic fatigue syndrome (CFS)?

Updated: Sep 20, 2018
  • Author: Burke A Cunha, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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The posterior oropharynx in patients with EBV infectious mononucleosis is uniformly erythematous. This is in contrast to the discreet pretonsillar purplish discoloration observed in chronic fatigue syndrome (CFS) that has been termed "crimson crescents." Crimson crescents, a possible marker of CFS, occur in the absence of surrounding posterior pharyngeal erythema. Patients with CFS do not present predominantly with pharyngitis.

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