What are the possible complications of high-dose quinine for the treatment of malaria?

Updated: Apr 26, 2019
  • Author: Thomas E Herchline, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Methemoglobinemia is a complication that may be associated with high-dose regimens of quinine or the derivatives chloroquine and primaquine. [24] A patient presenting with cyanosis and a normal PaO2 on room air should be suspected of having methemoglobinemia.


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