What is the role of clonidine in the treatment of spasticity?

Updated: Jun 28, 2019
  • Author: Krupa Pandey, MD; Chief Editor: Stephen A Berman, MD, PhD, MBA  more...
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Clonidine has shown efficacy for spasticity in open-label studies. It is a selective alpha2-receptor agonist and may inhibit presynaptic sensory afferents. Hypotension is the main adverse effect.

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