What is the role of immunoglobulin M (IgM) ELISA in the evaluation of leptospirosis?

Updated: Jul 08, 2021
  • Author: Sandra G Gompf, MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

An immunoglobulin M (IgM) enzyme-linked immunoabsorbent assay (ELISA) has been developed. The ELISA uses a broadly reactive antigen and is a standard serologic procedure, as is the MAT. [43] Because it detects IgM, it may be useful for diagnosis of new infections within 3-5 days. Positive results should be referred for confirmatory testing.


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