How can history be used to narrow the differential diagnoses of leptospirosis?

Updated: Jul 08, 2021
  • Author: Sandra G Gompf, MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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A possible key to correct diagnosis is a thorough history focusing on the patient's travel history, activities, and exposure to animals. Case clusters, if present, may suggest a common exposure.

Other problems to be considered may include the following:

  • Enteric fever
  • Infantile polyarteritis nodosa
  • Kawasaki disease
  • Primary HIV infection
  • Typhoid fever
  • Yellow fever
  • Mononucleosis
  • Cholecystitis
  • Pancreatitis and pancreatic pseudocyst

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