What are complications of leptospirosis?

Updated: Jul 08, 2021
  • Author: Sandra G Gompf, MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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The infection may progress to severe systemic inflammatory syndrome with hemorrhagic features. Findings of disseminated intravascular coagulation may occur with bleeding.

The onset of mental status alterations indicates progression to parenchymal involvement of the cerebral cortex with meningo-encephalitis, heralding a high mortality risk.

Severe and diffuse alveolar hemorrhage with massive hemoptysis can occur in the absence of typical Weil disease.

Myocarditis may occur in severe disease. All of the physical findings of biventricular heart failure can be found, including elevated jugular venous pulsations; a new S3 gallop; and dysrhythmias, including atrial fibrillation, heart blocks of varying severity, and ventricular ectopy.

Acalculous cholecystitis is a finding of profound systemic illness. Pancreatitis has also been described in severe cases.383940

Uveitis, iridocyclitis, and chorioretinitis may occur late into illness and may persist for years.

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