What are the clinical manifestations of leptospirosis?

Updated: Jul 08, 2021
  • Author: Sandra G Gompf, MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Particular serovars may be associated with specific clinical manifestations. For example, a characteristic pretibial erythematous rash is seen in patients with L autumnalis infection, and gastrointestinal symptoms predominate in patients infected with L grippotyphosa.

Nevertheless, any leptospiral serovar can lead to the signs and symptoms seen with this disease. For example, jaundice occurs in 83% of patients with L icterohaemorrhagiae infection and in 30% of patients infected with L pomona. Aseptic meningitis commonly occurs in those infected with L pomona or L canicola.

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