What should be included in long-term monitoring following treatment of leprosy?

Updated: Jun 05, 2020
  • Author: Darvin Scott Smith, MD, MSc, DTM&H; Chief Editor: Michael Stuart Bronze, MD  more...
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Once treatment is completed, the patient should be monitored for the next 5-10 years to evaluate for signs of relapse. The WHO defines relapse as marked increase in the bacillary index at any single site, usually accompanied by clinical deterioration. [24] To date, the relapse rate following completion of multidrug therapy has been around 1% for both types of leprosy. In such cases, new bacillus-positive lesions may develop and should be treated with a thorough US regimen that incorporates once-daily rifampin (see Treatment).

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