What is the role of pentamidine in the management of leishmaniasis?

Updated: Feb 18, 2020
  • Author: Craig G Stark, MD, FACP, FFTM, RCPS(Glasg), FISTM; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

Intramuscular pentamidine is effective against visceral leishmaniasis, but this drug is associated with persistent diabetes mellitus and disease recurrence. Pentamidine is the drug of choice to treat L (Viannia) guyanensis in French Guyana, where antimonial resistance is prevalent. [41]


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