What is the role of beta-lactam/beta-lactamase combination antibiotics in the treatment of Klebsiella infections?

Updated: Jun 10, 2019
  • Author: Shahab Qureshi, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
  • Print
Answer

Ceftazidime/avibactam is indicated to treat adults with complicated intra-abdominal infections (in combination with metronidazole) and complicated UTIs, including kidney infections (pyelonephritis), who have limited or no alternative treatment options. Ceftolozane/tazobactam and ceftazidime/avibactam are two novel beta-lactam/beta-lactamase combination antibiotics available. Ceftazidime/avibactam is also active against carbapenem-resistant Enterobacteriaceae that produce K pneumoniae carbapenemases. [14]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!