Which factors increase the risk of Klebsiella colonization and infection?

Updated: Jun 10, 2019
  • Author: Shahab Qureshi, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Host factors that lead to colonization and infection include the following:

  • Hospitalization (especially admission to an intensive care unit)

  • Immunocompromised states (eg, diabetes, alcoholism)

  • Antimicrobial therapy

  • Prolonged use of invasive medical devices

  • Inadequate infection control practices

  • Severe illness, including major surgery

The organism gains access to the body either by direct inoculation through breached epithelial surfaces or following aspiration of oropharyngeal organisms.


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