In which settings are patients at highest risk of Klebsiella pneumoniae carbapenemase (KPC) transmission?

Updated: Jun 10, 2019
  • Author: Shahab Qureshi, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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An investigation of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae among patients of acute and long-term acute care hospitals was conducted in 2011. The investigation found extensive spread of KPC-producing Enterobacteriaceae throughout 4 adjacent counties in Indiana and Illinois over a 1-yr period. Long-term acute care hospitals played a central role in the outbreak, suggesting that guidelines for controlling KPC should be expanded to include long-term care facilities. Education of personnel and coordinated regional efforts among health care facilities are crucial for KPC control. [7]

Another multihospital study on transmission risk found that patients admitted to acute care hospitals from high-acuity long-term–care facilities were more likely to be colonized with KPC-producing Enterobacteriaceae than were patients admitted from the community. [8]

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