What causes granuloma inguinale (donovanosis) and what is the incidence in the US?

Updated: Jun 10, 2019
  • Author: Shahab Qureshi, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Klebsiella granulomatis (formerly Calymmatobacterium granulomatis) is a fastidious member of the genus that causes chronic genital ulcerative disease also known as granuloma inguinale or donovanosis. It is a relatively rare disease in the United States, with fewer than 100 cases reported annually. It has long been a recognized cause of genital ulceration in parts of India, Papua New Guinea, the Caribbean, and South America (particularly Brazil). Fortunately, the incidence of the disease has decreased in recent years.

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