Which medications in the drug class Vaccines, Live, Viral are used in the treatment of Influenza?

Updated: Apr 23, 2019
  • Author: Hien H Nguyen, MD, MS; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Vaccines, Live, Viral

Influenza vaccine is administered each year before flu season. The FDA makes the final decision about vaccine strains for influenza vaccines to be sold in the United States, based on year-round surveillance conducted by the CDC and the WHO. [8]

The Advisory Committee on Immunization Practices (ACIP) recommends return of intranasal flu vaccine in the United States for the 2018-2019 season. The recommendation was based on positive results from a US study in children aged 2 years to younger than 4 years that evaluated the shedding and antibody responses of the H1N1 strain in the live attenuated influenza vaccine (LAIV). The study showed that the new 2017-2018 H1N1 LAIV postpandemic strain (A/Slovenia) performed significantly better than the 2015-2016 H1N1 LAIV postpandemic strain (A/Bolivia), which was associated with lower effectiveness and was not recommended during the prior 2 seasons. [55]

LAIV4 was not recommended during the 2017-2018 or 2016-2017 influenza seasons because it was poorly effective against circulating strains of influenza in the United States. [51, 57, 58]

Influenza virus vaccine quadrivalent, intranasal (FluMist Quadrivalent)

Indicated for active immunization to prevent influenza A and B.


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