How is influenza prevented during pregnancy?

Updated: Aug 07, 2020
  • Author: Hien H Nguyen, MD, MS; Chief Editor: Michael Stuart Bronze, MD  more...
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A CDC analysis stressed the importance of vaccinating pregnant women regardless of trimester and prompt treatment with a neuraminidase inhibitor (ie, within 2 days of symptom onset) if influenza occurs during pregnancy. [55] Vaccination of high-risk pregnant patients also provides some protective immunity for newborns and reduces subsequent hospitalizations in the infants. [56]

A case-control study by Thompson et al supported previous evidence that seasonal trivalent inactivated influenza vaccine reduces the risk of acute respiratory illness (ARI) by more than half in pregnant women with laboratory-confirmed influenza infection. In the study, which was conducted over 2 flu seasons (2010-2011 and 2011-2012), 42 pregnant women with influenza who had been vaccinated during flu season were compared with over 110 vaccinated controls with ARI but no influenza infection and 126 matched, vaccinated controls with no ARI. [57, 58]

The CDC recommends influenza vaccine be administered during pregnancy (all trimesters); vaccination during pregnancy shown to decrease risk of illness in the mother, as well as the risk of influenza and influenza hospitalization in their infants during the first 6 months of life. [59]

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