What increases the risk of severe influenza?

Updated: Apr 23, 2019
  • Author: Hien H Nguyen, MD, MS; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Diabetes increases the risk of severe flu-related illness. In a cohort study of 166,715 individuals in Manitoba, Canada, Lau and colleagues found that adults with diabetes are at significantly greater risk for serious illness related to influenza compared with those without diabetes; this justifies guideline recommendations for influenza vaccination in this population. After controlling for age, sex, socioeconomic status, location of residence, comorbidities, and vaccination, adults with diabetes had a significant increase (6%) in all-cause hospitalizations associated with influenza (P = .044). Only 16% of the patients with diabetes in the cohort and 7% of the patients without diabetes had been vaccinated. [26, 27]


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