Which medications in the drug class Vaccines, Inactivated, Viral are used in the treatment of Human Papillomavirus (HPV)?

Updated: Feb 20, 2020
  • Author: Peter A Gearhart, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Vaccines, Inactivated, Viral

The 9-valent HPV vaccine is indicated for prevention of HPV-associated neoplasias and precancerous genital lesions. The 2-valent and 4-valent vaccines were discontinued from the US market in 2016.

Children and adolescents aged 15 years and younger need 2, not 3, doses of the HPV vaccine; this ACIP recommendation stems from the vaccine’s enhanced immunogenicity in preteens and adolescents aged 9-14 years. The immunization schedule for older adolescents and young adults aged 15-45 years is 2-3 inoculations (depending on immunization history) within 6 months. [92]

Human papillomavirus vaccine, nonavalent (Gardasil 9)

Induces humoral immune response to 9 HPV subtypes: 6, 11, 16, 18, 31, 33, 45, 52, and 58. It is indicated for routine immunization in males and females aged 9-26 years to prevent HPV-associated diseases. Immunization for adults aged 27-47 years is based on shared decision making between the patient and clinician.

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