What are possible limitations of the human papillomavirus (HPV) vaccine?

Updated: Feb 20, 2020
  • Author: Peter A Gearhart, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Some research groups remain skeptical of the value of the HPV vaccine, arguing that the design of the relevant clinical trials and the interpretation of the efficacy and safety data have not been sufficiently rigorous and that vaccines have not actually been shown to prevent a single case of cervical cancer. From this perspective, it might be preferable to focus on cervical screening and targeting other factors of the disease rather than on vaccination.

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