What is the efficacy of quadrivalent vaccines against human papillomavirus (HPV) infection in females?

Updated: Feb 20, 2020
  • Author: Peter A Gearhart, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

In a double-blinded placebo-controlled trial that tested a quadrivalent HPV vaccine (HPV types 6, 11, 16, and 18) in 277 young females who were observed on average for 3 years, women who received the vaccine had a 90% reduction in infection with these 4 HPV types in comparison with females who received placebo. [99] Other studies have also yielded good results, [100, 101] but further data on the safety of the vaccine and the longevity of immune responses to the vaccine are still needed.


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