What is the prognosis of human papillomavirus (HPV) infection following cryosurgery?

Updated: Feb 20, 2020
  • Author: Peter A Gearhart, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

After 2-4 treatments in a 6- to 12-week period, 75-80% of patients experience a complete clearing of warts. Data from several clinical trials reported a 63-88% clearance 3 months after therapy. A trial evaluating cryotherapy alone against cryotherapy combined with podophyllotoxin failed to demonstrate an improved outcome with the combination therapy. [86] The recurrence rate (22%) is similar to that of electrosurgery.


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