What is the role of cervical metaplasia in the of human papillomavirus (HPV) infection?

Updated: Feb 20, 2020
  • Author: Peter A Gearhart, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

Although cervical metaplasia is prevalent among sexually active adolescents, placing them at increased risk for HPV infection, immune system clearance within 1-2 years is common. In addition, invasive cervical cancer is rare among adolescents, and most cervical dysplasias resolve spontaneously. While some studies have suggested women undergoing excisional procedures for cervical dysplasia have an increased risk of preterm births, a 2012 study by Kalliala et all suggests excisional procedures do not appear to increase preterm birth risk. [61] Because adolescents have most of their childbearing years ahead of them, however, delaying cervical cancer screening may be a prudent strategy in this population.


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