What are the clinical manifestations of human papillomavirus (HPV) infections?

Updated: Feb 20, 2020
  • Author: Peter A Gearhart, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Infections due to HPV are common and lead to a wide variety of clinical manifestations that involve the epidermal surfaces. Condylomata acuminata (genital warts) are generally recognized as benign proliferations of the anogenital skin and mucosa resulting from HPV infection. Genital warts are transmitted by sexual contact. Approximately two thirds of individuals who have sexual contact with an infected partner develop genital warts. The exact incubation time is unknown but estimated to be 3 weeks to 8 months. [6, 7]

Despite the generally benign nature of these proliferations, certain types of HPV can place patients at a high risk for anogenital cancer. [8, 9, 10] Some have also been implicated in laryngeal and oral cancer and some lung cancers.

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