When is a biopsy indicated for the diagnosis of human papillomavirus (HPV) infection?

Updated: Feb 20, 2020
  • Author: Peter A Gearhart, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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In some cases, tissue biopsy can be used to confirm HPV infection. A biopsy is recommended for the following scenarios:

  • Women with a history of vulvar dysplasia

  • Postmenopausal women

  • Women in whom medical therapy fails

  • Clinical doubt about the diagnosis

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