What is the role of methylene blue in the treatment of calcium channel blocker (CCB) toxicity?

Updated: Jan 04, 2021
  • Author: B Zane Horowitz, MD, FACMT; Chief Editor: Michael A Miller, MD  more...
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Experimental use of methylene blue in distributive shock has prompted its consideration in calcium channel blocker overdose with cardiogenic shock. Case reports describe successful use in CCB overdose refractory to other therapies, at a starting dose of 1–2 mg/kg IV. [59, 60]

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