When is hospitalization indicated for the management of calcium channel blocker (CCB) toxicity in adults?

Updated: Jan 04, 2021
  • Author: B Zane Horowitz, MD, FACMT; Chief Editor: Michael A Miller, MD  more...
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Answer

Adult referral amounts for accidental extra dosing are as follows:

  • Amlodipine: >10 mg
  • Bepridil: >300 mg
  • Diltiazem immediate release: >120 mg
  • Diltiazem sustained release: >360 mg swallowed or >120 mg if chewed or unknown
  • Diltiazem extended release: >540 mg
  • Felodipine: >10 mg
  • Isradipine: >20 mg
  • Nicardipine immediate release: >40 mg
  • Nicardipine sustained release: >60 mg swallowed or >40 mg if chewed or unknown
  • Nifedipine immediate release: >30 mg
  • Nifedipine sustained release: >120 mg swallowed or >30 mg if chewed or unknown
  • Nimodipine: >60 mg
  • Nisoldipine: >30 mg
  • Verapamil immediate release: >120 mg
  • Verapamil sustained release: >480 mg swallowed or >120 mg if chewed or unknown

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