What is the role of vitamin D in the treatment of resorptive hypercalciuria and hyperparathyroidism?

Updated: Apr 23, 2019
  • Author: Stephen W Leslie, MD, FACS; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Paricalcitol is a vitamin-D analogue that was developed to help prevent and treat secondary hyperparathyroidism in patients with chronic renal failure. Actual vitamin D also suppresses parathyroid hormone levels but tends to cause hypercalcemia and hyperphosphatemia. Vitamin-D analogues such as paricalcitol are able to significantly reduce PTH levels without significantly changing serum levels or urinary excretion of either calcium or phosphorus.


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