How is hypercalciuria defined?

Updated: Apr 23, 2019
  • Author: Stephen W Leslie, MD, FACS; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Hypercalciuria is defined as urinary excretion of more than 250 mg of calcium per day in women or more than 275-300 mg of calcium per day in men while on a regular unrestricted diet. It can also be defined as the excretion of urinary calcium in excess of 4 mg/kg of body weight per day or as a urinary concentration of more than 200 mg of calcium per liter.

An alternate definition of hypercalciuria is daily urinary excretion of more than 3 mg of calcium per kilogram of body weight or more than 200 mg of calcium per day, while on a restricted diet (400 mg calcium and 100 milliequivalent [mEq] sodium). Table 1, below, outlines the various definitions of hypercalciuria based on a regular or restricted diet.

Table 1. Definitions of Hypercalciuria (Open Table in a new window)

Diet

Definition

Regular diet (unrestricted)

Women: Urinary excretion >250 mg calcium (6.2 mmol/24 h)

Men: Urinary excretion >275-300 mg calcium (7.5 mmol/24 h)

Urinary excretion >4 mg calcium (0.1 mmol) per kilogram of body weight per day

Urinary concentration >200 mg calcium per liter

Restricted diet (400 mg calcium, 100 mEq sodium)

Urinary excretion >200 mg calcium per day

Urinary excretion >3 mg calcium per kilogram of body weight per day


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