How is cellulitis treated in patients with Haemophilus influenzae infections?

Updated: Jun 11, 2021
  • Author: Joseph Adrian L Buensalido, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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In patients with Hib cellulitis, administer parenteral antibiotics until the patient shows defervescence and the cellulitis subsides. Then, administer appropriate oral antibiotics until the course of therapy, usually 7-10 days, is finished. Empiric therapy for preseptal cellulitis should cover not only Hib but also S pneumoniae, Staphylococcus aureus, and group A beta-hemolytic streptococci. Hib was once one of the most common pathogens in preseptal and orbital cellulitis in children before the Hib vaccine became widely administered. [92]

Patients with orbital cellulitis should receive at least 14 days of inpatient parenteral therapy. Upon hospital discharge, the intravenous antibiotic should be switched to oral (eg, amoxicillin-clavulanate) and continued for an additional 1-3 weeks. [93]

Surgical drainage may be needed for the underlying sinusitis or for orbital abscesses.

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