What are the trends in Haemophilus influenzae infection rates in the US?

Updated: Jul 02, 2019
  • Author: Joseph Adrian L Buensalido, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

In 2006, the Active Bacterial Core Surveillance Report for H influenzae infection reported the following prevalences in 10 studied states (with a total study population of 35,599,550 persons):

  • Hib infection - 0.04 cases per 100,000 general population
  • Non-Hib infection - 0.36 cases per 100,000 general population
  • NTHi infection - 0.99 cases per 100,000 general population (NTHi infections accounted for 353 of the 551 H influenzae infection cases reported in this series. [9] )

The latest Active Bacterial Core Surveillance Report for H influenzae infection in 2015 reported the following prevalence rates in 10 studied states (with a total study population of 43,912,887 persons):

  • Hib infection: 0.02 cases per 100,000 general population
  • Non-Hib infection: 0.42 cases per 100,000 general population
  • NTHi infection: 1.24 case per 100,000 population (NTHi infections accounted for 544 of the 822 H influenzae infection cases reported in this series. [10] )

Meanwhile, the prevalence of Hia infections has increased in some countries since the advent of the Hib conjugate vaccine. However, in the United States, the number of Hia infections reported has remained constant. [11, 12]


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