What are the CDC treatment guidelines for gonorrhea?

Updated: Sep 07, 2018
  • Author: Brian Wong, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

The CDC treatment guidelines on gonorrhea infections are as follows: [1]

  • Uncomplicated gonorrhea infections of the urethra, cervix, pharynx, and rectum: Ceftriaxone 250 mg IM as a single dose plus azithromycin 1 g PO as a single dose
  • Gonococcal conjunctivitis: Ceftriaxone 250 mg IM as a single dose plus azithromycin 1 g PO as a single dose
  • Disseminated gonococcal infections with arthritis and/or dermatitis: Ceftriaxone 1 g IV or IM every 24 hours plus azithromycin 1 g PO as a single dose
  • Gonococcal meningitis and endocarditis: Ceftriaxone 1-2 g IV every 12-24 hours plus azithromycin 1 g PO as a single dose

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