What are the WHO treatment guidelines for gonococcal conjunctivitis in neonates?

Updated: Jun 15, 2021
  • Author: Shahab Qureshi, MD, FACP; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

In neonates with gonococcal conjunctivitis, the WHO STI guidelines suggest one of the following treatment options:

  • Ceftriaxone 50 mg/kg (maximum 150 mg) IM as a single dose  or
  • Kanamycin 25 mg /kg (maximum 75 mg) IM as a single dose  or
  • Spectinomycin 25 mg/kg (maximum 75 mg) IM as a single dose

For ocular prophylaxis, the WHO guidelines suggest one of the following options for topical application to both eyes immediately after birth:

  • Tetracycline hydrochloride 1% eye ointment  or
  • Erythromycin 0.5% eye ointment  or
  • Povidone iodine 2.5% solution (water-based)  or
  • Silver nitrate 1% solution  or
  • Chloramphenicol 1% eye ointment

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