What are the WHO guidelines for retreatment of gonorrhea after treatment failure?

Updated: Sep 07, 2018
  • Author: Brian Wong, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

If treatment failure occurs after a WHO recommended dual therapy, re-treat with one of the following dual therapies:

  • Ceftriaxone 500 mg IM as a single dose plus azithromycin 2 g PO as a single dose or
  • Cefixime 800 mg orally as a single dose plus azithromycin 2 g PO as a single dose or
  • Gentamicin 240 mg IM as a single dose plus azithromycin 2 g PO as a single dose or
  • Spectinomycin 2 g IM as a single dose (if not an oropharyngeal infection) PLUS azithromycin 2 g PO as a single dose

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