What are the treatment options for gonorrhea?

Updated: Jun 15, 2021
  • Author: Shahab Qureshi, MD, FACP; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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For uncomplicated urogenital, anorectal, and pharyngeal gonococcal infection, a drug regimen using ceftriaxone plus either azithromycin or doxycycline may be used. Antimicrobial drugs used alone or in various combinations in other gonococcal infections include the following:

  • Gonococcal arthritis: Ceftriaxone

  • Gonococcal conjunctivitis: Ceftriaxone

  • Gonorrhea contributing to PID: Cefoxitin, ceftriaxone, doxycycline, metronidazole, cefotetan, clindamycin, gentamicin

  • Gonococcal epididymitis: Ceftriaxone, doxycycline

  • DGI: Ceftriaxone, cefotaxime, ceftizoxime

  • Gonococcal meningitis and endocarditis: Ceftriaxone

See Treatment and Medication for more detail.

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