Which oral anticoagulants (OAC) are used for stroke prevention in atrial fibrillation (AF)?

Updated: Feb 27, 2020
  • Author: Tarek Ajam, MD, MS; more...
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Atrial fibrillation (AF) is a cardiac arrhythmia with the potential to cause thromboembolism. Studies suggest that AF increases the risk of stroke five-fold. [1]  Thus, it is important to determine which patients with AF may benefit from oral anticoagulant (OAC) and possibly aspirin therapy to reduce the risk of stroke. OACs used in this setting include the following medications for stroke preventions in atiral fibrillation:

  • Warfarin, with a goal International Normalized Ratio (INR) of 2-3 and percent time in therapeutic INR (TTR) remains ≥ 70%
  • Dabigatran
  • Rivaroxaban
  • Apixaban
  • Edoxaban

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