Which empirical therapy regimens are used for eradication of Helicobacter pylori infection?

Updated: Dec 09, 2020
  • Author: Joseph Adrian L Buensalido, MD; more...
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Regimens for eradication of Helicobacter pylori infection are typically chosen empirically, on the basis of regional bacterial resistance patterns, local recommendations, and drug availability. [1]  Health care providers should ask their patients about any prior antibiotic use or exposure, and take that information into consideration before choosing a treatment regimen. [2]  The following regimens are described below [3] :

  • Triple therapy
  • Nonbismuth quadruple therapy
  • Bismuth-based therapy
  • Levofloxacin-containing therapy
  • Concomitant bismuth and levofloxacin-containing therapy
  • Second-line therapy
  • Rescue or third-line therapy

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