Which types of exposures may require occupational HIV postexposure prophylaxis (PEP)?

Updated: Nov 14, 2019
  • Author: Jason F Okulicz, MD, FACP, FIDSA; more...
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An exposure that might place a health care provider at risk for HIV infection is defined as one of the following:

  • Percutaneous injury (eg, a needlestick or cut with a sharp object)
  • Contact of mucous membrane or nonintact skin (eg, exposed skin that is chapped, abraded, or afflicted with dermatitis)

In addition to blood and visibly bloody body fluids, the following fluids are considered potentially infectious:

  • Semen and vaginal secretions
  • Cerebrospinal fluid
  • Synovial fluid
  • Pleural fluid
  • Peritoneal fluid
  • Pericardial fluid
  • Amniotic fluid

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