How is enteroviral myopericarditis treated?

Updated: Mar 17, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
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Treatment is mainly supportive in nature and involves management of pericardial pain, pericardial effusion, arrhythmias, and heart failure.

Bed rest is important since exercise can increase the degree of myocardial necrosis.

Intravenous immunoglobulin (IVIG) therapy has shown some benefit in small case-control studies. Nevertheless, most reports lack statistical significance, and randomized trials are needed. [69, 70]

Capsid-binding inhibitors belong to a class of drugs that have shown benefit in some immunosuppressed patients with myocarditis. However, these drugs are not available for use in the United States. [71]

Corticosteroids yield little or no benefit, and immunosuppressive therapy is contraindicated during the acute phase of viral myocarditis because they have been shown to cause clinical deterioration. [72]

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