When is tigecycline used to treat enterococcal infections?

Updated: Jun 10, 2021
  • Author: Susan L Fraser, MD; Chief Editor: John L Brusch, MD, FACP  more...
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Tigecycline, a glycylcycline antibiotic released in 2005, can be used to treat gram-positive, gram-negative, and anaerobic bacterial infections. It can be used to treat vancomycin-sensitive E faecalis infections, and, although it has in vitro activity against E faecium and VRE (including E casseliflavus and E gallinarum), as with daptomycin, clinical data are limited. Newer tetracycline antibiotics that may be considered for enterococcal infections include omadacycline and eravacycline, although in many cases usage would be off-label.

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