Which medications in the drug class Tetracyclines are used in the treatment of Enterococcal Infections?

Updated: Jun 10, 2021
  • Author: Susan L Fraser, MD; Chief Editor: John L Brusch, MD, FACP  more...
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Omadacycline (Nuzyra)

Omadacycline is indicated for the treatment of adult patients with acute bacterial skin and skin structure infections caused by several different susceptible organisms including Enterococcus faecalis. Although it has in vitro activity against Enterococcus faecium, including vancomycin resistant strains, it has not been approved to treat infections due to this species. It is available in both intravenous and oral formulations.

Eravacycline (Xerava)

Eravacycline is a fluorocycline indicated for the treatment of complicated intra-abdominal infections caused by many susceptible microorganisms including both Enterococcus faecalis and Enterococcus faecium (including VRE if in vitro susceptibility testing is available). It is not indicated for the treatment of complicated urinary tract infections or for endocarditis. It is available only for injection.

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