How do metallo-beta-lactamases affect the treatment of Enterobacter infections?

Updated: Jun 18, 2019
  • Author: Susan L Fraser, MD; Chief Editor: Michael Stuart Bronze, MD  more...
  • Print
Answer

Metallo-beta-lactamases cause resistance across the carbapenem class, are transmissible, and have been associated with clinical outbreaks in hospitals worldwide. In one reported outbreak of 17 cases of infection (2 due to Enterobacter species), molecular studies demonstrated presence of a gene belonging to bla(VIM-1) cluster. [38] KPC-type carbapenemases have emerged in New York City. [24] The new NDM-1 carbapenemase has already rapidly spread to many countries. [12]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!