What is the role of antibiotics in the treatment of Enterobacter infections?

Updated: Jun 18, 2019
  • Author: Susan L Fraser, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Antimicrobial therapy is indicated in virtually all Enterobacter infections. With few exceptions, the major classes of antibiotics used to manage infections with these bacteria include the following:

  • Beta-lactams: Carbapenems are the most reliable beta-lactam drugs for the treatment of severe Enterobacter infections; fourth-generation cephalosporins are a distant second choice
  • Aminoglycosides: Aminoglycoside resistance is relatively common and varies widely among centers
  • Fluoroquinolones: Resistance to fluoroquinolones is increasing and may be very high in some parts of the world
  • Trimethoprim-sulfamethoxazole (TMP-SMZ): Resistance to TMP-SMZ is more common

See Treatment and Medication for more detail.


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