What are the less common signs and symptoms of infective endocarditis (IE)?

Updated: Jan 03, 2019
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Signs of neurologic disease occur in as many as 40% of patients. Embolic stroke with focal neurologic deficits is the most common etiology. Other etiologies include intracerebral hemorrhage and multiple microabscesses. [1]

Signs of systemic septic emboli are due to left heart disease and are more commonly associated with mitral valve vegetations. Multiple embolic pulmonary infections or infarctions are due to right heart disease.

Signs of congestive heart failure, such as distended neck veins, frequently are due to acute left-sided valvular insufficiency.

Splenomegaly may be present.

Other signs include the following:

  • Stiff neck

  • Delirium

  • Paralysis, hemiparesis, aphasia

  • Conjunctival hemorrhage

  • Pallor

  • Gallops

  • Rales

  • Cardiac arrhythmia

  • Pericardial rub

  • Pleural friction rub

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