What are features of microorganisms that commonly produce infective endocarditis (IE)?

Updated: Jan 03, 2019
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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The microorganisms that most commonly produce endocarditis (ie, S aureus; Streptococcus viridans; group A, C, and G streptococci; enterococci) resist the bactericidal action of complement and possess fibronectin receptors for the surface of the fibrin-platelet thrombus. Among the many other characteristics of IE-producing bacteria demonstrated in vitro and in vivo, some features include the following:

  • Increased adherence to aortic valve leaflet disks by enterococci, S viridans, and S aureus

  • Mucoid-producing strains of S aureus

  • Dextran-producing strains of S viridans

  • S viridans and enterococci that possess FimA surface adhesin

  • Platelet aggregation by S aureus and S viridans and resistance of S aureus to platelet microbicidal proteins

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