What is the treatment for an asymptomatic pulmonary nodule in coccidioidomycosis?

Updated: Aug 27, 2019
  • Author: Duane R Hospenthal, MD, PhD, FACP, FIDSA, FASTMH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Antifungal therapy for asymptomatic pulmonary nodules is not typically recommended in immunocompetent patients. Most lesions do not require any further investigation, especially if they are unchanged on serial imaging for 2 or more years. If the nodule starts enlarging, measure coccidial serum antibodies to determine whether disease has become active, which warrants therapy. Resection is indicated if no diagnosis is established and malignancy is a concern.


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