What are the treatment options for uncomplicated acute pneumonia in coccidioidomycosis?

Updated: Aug 27, 2019
  • Author: Duane R Hospenthal, MD, PhD, FACP, FIDSA, FASTMH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Typical antifungal therapy of acute primary pulmonary coccidioidomycosis in these high-risk groups consists mainly of oral azoles at the recommended adult doses (see Medication). During pregnancy, amphotericin B is the treatment of choice because the azoles may be teratogenic.

No consensus has been reached on the duration of therapy, but 6 months of treatment is most common, and CF IgG titers are used to monitor response to therapy. Periodic follow-up is recommended for up to 1 year or longer.


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